Đánh giá đáp ứng miễn dịch của hai loại vaccine nhược độc chủng M.B. phòng bệnh Gumboro trên gà ác
* Người chịu trách nhiệm về bài viết: Nguyễn Thị Kiều Oanh (email: [email protected])
Abstract
This study aimed to evaluate the immune response of two attenuated M.B. A total of 135 one-day-old Ác chicken were arranged in a completely randomized design with one factor coming in 2 groups (1) vaccination with MB-1 at 1 one-day-old in the hatchery; and (2) vaccination with live MB vaccine at 7 and 15 days old at the farm. Chickens were blooded at 1, 14, 21, 24, 28 days old to check IBD antibody titer. In addition, bursa index (BI), body weight, and daily weight gain of chickens from 1-49 days old were also monitored. The results showed that the maternal antibody against IBD virus of the flock was 1515 titers with a CV of 58.7%. On 14, 21, 24 days old, antibody titer IBD between the two group was not statistically different (P > 0.05). By 28 days old, antibody titer IBD of MB-1 group was significantly higher than antibody titer of MB live group, 6218 titer and 5075 titer (P < 0.05). The BI, body weight, and daily weight gain of the MB-1 group tended to be higher than the MB live group over time.
Tóm tắt
Nghiên cứu nhằm đánh giá đáp ứng miễn dịch của hai loại vaccine nhược độc chủng M.B. Một trăm ba mươi lăm gà Ác 1 ngày tuổi được bố trí hoàn toàn ngẫu nhiên một yếu tố vào 2 lô gồm (1) tiêm vaccine MB-1 lúc 1 ngày ở trạm ấp và (2) chủng vaccine MB live lúc 7 và 15 ngày ở trại. Gà được lấy máu lúc 1, 14, 21, 24, 28 ngày để kiểm tra hiệu giá kháng thể (HGKT) IBD. Các chỉ số túi Bursa (BI), khối lượng bình quân (KLBQ) và tăng trọng hàng ngày (TTHN) của gà từ 1 đến 49 ngày cũng được theo dõi. Gà con có HGKT mẹ truyền kháng virus IBD là 1515 titer với CV 58,7%. Vào thời gian 14, 21, 24 ngày, HGKT IBD giữa hai lô không có khác biệt về mặt thống kê (P > 0,05). Đến 28 ngày, HGKT IBD của lô MB-1 cao hơn có ý nghĩa so với HGKT lô MB live, 6218 titer so với 5075 titer (P < 0,05). Các thông số BI, KLBQ, TTHN của lô MB-1 có xu hướng cao hơn so với lô MB live qua các thời điểm.
Article Details
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